Tuesday, October 8, 2013

Cialis and Its Variant: Generic Cialis

Cialis (Tadalfil) is in a class of drugs called phophodiesterase inhibitors. FDA approved Tadalfil - Cialis in 2003 for the treatment of men who experience difficulty having and maintaining an erection.
Cialis (Tadalfil), an oral treatment for Erectile Dysfunction (ED) in men, is a selective inhibitor of cyclic quanosine monophosphate (cGMP) - specific phophodiesterase type 5 (PDE 5).
Cialis is available in the form of tablets which contains 5, 10 or 20 mg of Tadalfil and inactive ingredients like croscarmellose sodium, hydroxpropyl cellulose, hypromellose, iron oxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulphate, talc, titanium dioxide and triacetin.
Recommended dose of Cialis in most patients is 10mg taken prior to sexual intercourse. Both Cialis and Viagra work in the same way, by helping blood vessels in the penis to relax allowing blood to flow into the penis causing an erection.
Cialis is slightly different from the other ED drugs available in the market as it may work up to 36 hrs after dosing.
Cialis is available online with various sites offering cheap Cialis. Forzest is the Indian answer to Cialis and is manufactured by Ranbaxy Laboratories Ltd. Forzest is same as Tadalfil and is also known as Generic Cialis.
When a doctor prescribes and while buying it on the net there may be a choice between a brand - name medicine and the generic version of that medicine.
Generic Cialis is available online and one can buy generic Cialis from these legal sites. There are variants of Generic Cialis available in the market - they are called generic Cialis or generic Tadalfil. They have the same composition as the branded Cialis. One can buy generic drugs as they only may look different because in the US, FDA does not allow it to look the same. Colors, flavors and certain other inactive ingredients may be different but the core ingredient remains the same.
As most of the drugs fall under the patent law many companies are lining up to manufacture generic forms of the brand name drugs going off patent. Many Indian companies are in the race for regulatory approval to introduce medicines in the highly lucrative North American market.
Many Chinese companies are also scaling up capabilities so that they could also foray into the generic market. All these companies need to file DMFs (drug masters file) before the US FDA detailing confidential information about manufacturing, processing and storing of drugs. They contain information about what is usually referred to as the active pharmaceutical ingredient (API), the core component of a drug. DMFs are also meant to support abbreviated new drug applications (ANDA). An ANDA approval is required to register generic versions of patented medicines that generate huge potential for what are often called 'copycats' of the drugs going off patent.

Cialis-more Arguments in Its Favor

Many arguments have been used in order to improve the image of Viagra or, in the contrary to steady the image of another product of this range which is called Cialis. Starting from the period of time it lasts in your body( four hours in the case of Viagra or two days in what Cialis is concerned) and even the effects it produces over men suffering from diabetes( when it was claimed that Cialis, besides having great effects, it doesn't affect the blood glucose control). We have reached the conclusion that claiming Cialis is better then Viagra, can turn out to be true and here are more arguments in favor of this idea:
When using Cialis as treatment for erectile disfunctions, let's say a tablet each day for instance, and than continues the treatment, will observe that in the second day approximately twenty percent of the first tablet is still persisting in your body. On the fourth day twenty two percent of the original doze will still remain and on the sixth day around twenty four percent of than one pill taken in the beginning of the process is still there, laying intact. As a result, a person who has realized that the first doze of Cialis is still running the effects on after thirty six hours, can be sure of the fact that a doze each day could result in performing a healthy and trouble less active sexual life.
It is natural that Cialis should also develop side effects in some cases which can be as serious and as harmful for the body as any other pill taken unappropriately.It has been discovered that after one doze of Cialis, fourteen percent of the men suffer from headaches and nine percent experience even heart burns. Despite this fact, if you are considering of using Cialis in this way, you should definitely do it under extreme medical surveillance.
People from France are used to naming Cialis the ,weekend' medication, as, unlike Viagra which is compulsory to be taken on an empty stomach, Cialis has nothing to do with food and alcohol. In USA a mass production of Levitra and Cialis has been banned-or at least tried so_ but, taking into account that a similar action taken in Europe wasn't possible because of public opinion, maybe this will the case of America too.
Another point to be considered, in what concerns Cialis or any other similar drug, is whether it plays a role in providing sexual functions for women as well. Many cases and actions have ended in total failure as the sexual system at women is far more complex: for developing a satisfactory and fulfilling sexual life, women need more than just medication, which is the exact case of men.
All things considered, we may as well claim that Cialis can and will become the most sold product of this range for the simple fact that the experts who have created it, have thought about more important aspects than just performing the so waned erection. It is more of that to think about and so they did.

Musings On Cialis: How Is It Different From Other Erectile Dysfunction Drugs?

The mechanism of the FDA approved anti-impotency drugs discovered till date is similar in the sense that all of them inhibit phosphodiesterase type 5(PDE5) enzyme and increase blood flow to the penis which further assist the patient to trigger off erections required for satisfactory physical intercourse. But leaving aside the functioning process of the anti-impotency medications, each and every one of them has certain special attributes that mark their own individuality.
Turning the focus of the discussion over to Cialis, it is worth mentioning that the drug is different from other anti-impotency medicines for the fact that it works on the body for a full 36 hours and as such the erectile dysfunction patients can administer Cialis in the morning and prepare themselves for nocturnal revelry. Due to this specific Cialis advantage, Cialis usage remains a secret and the patients falling in the grip of male impotency are further emboldened to carry on with their anti-impotency regimen.
The other specific Cialis benefits that make your Cialis regimen far more advantageous are detailed below:
  • You can pop up Cialis pills on an empty as well as on a full stomach. A diet high with fats cannot influence Cialis effects in the system.
  • Due to the enormous popularity of Cialis around the world, floodgates of information on Cialis is easily available online and you can easily access the extensive tidbits on the drug by logging into an authentic Cialis pharmacy straight from your home.
As far as the expenses incurred in the purchase of Cialis [http://www.buy-cialis-online-now.com/cialis_myths.html] is concerned, the cost of Cialis is not high at all. In comparison to other anti-impotency medicines, Cialis is comparatively cheaper and hence it is also addressed as cheap Cialis.

Generic Cialis Enhances Sexual Performances for the Better

Cialis is an erectile dysfunction treatment drug to let a male get out of it. The introduction of the drug in the metabolism increases the blood flow to the penile tissues. The increase in the blood flow aids natural sexual stimulation in maintaining penile hardness and erection. As hardness of the organ is necessary in having a fulfilling sexual encounter, intake of Cialis pills prove it in a long way.
There are two forms of Cialis ED treatment pills viz. Brand Cialis and Generic Cialis. Both these form of Cialis helps a male perform during sexual encounter. However, cost of generic Cialis is lower than the cost of brand Cialis. As such, intake of this drug means availing a low cost drug with a power to let the male perform his best in bed.
Intake of generic Cialis pills should be considered only with the consultation of a doctor or health professional. It is a prescription drug thus availing prescription for the drug is necessary before starting its dosage. Anxiety, stress, lack of interest in sex, depression may also result in erectile dysfunction. Generic Cialis pills are just for increasing the blood flow to the penile tissues and it cannot help in aiding an individual to increase sexual stimulus.
The effectiveness of generic Cialis is of same quality as of brand Cialis. It is also able to show its effectiveness for duration of up to thirty-six hours after its consumption. However, patients with ED should be aware of side effects that can come along with its intake. Headache, myalgia, back pain, nasal congestion, and dyspepsia are some of the more frequent side effects that can occur due to the intake of generic Cialis.
Generic Cialis thus is a drug that enhances the sexual performance of males if the individual is suffering from erectile dysfunction. This pill lets its user attain sexual satisfaction without give rise to any complications. Though some side effects may be visible during initial period of its intake, it should cede once body adapts to its use. Generic Cialis is a prescription medicine thus requires prescription from a doctor to start its usage. Children, women, and individuals above 65 years should not use this drug.
A patient can easily buy generic Cialis from a number of online stores. These online stores lend the patient various discounts. With these discounts in hand on generic Viagra, a patient can enhance sexual performances.

Cialis - Lilly ICOS Wonder Drug

A slow and steady revolution is sweeping the market for erectile dysfunction drugs - Cialis. Most people may not even be aware of it. Lilly ICOS, the pharmaceutical alliance, which launched the blockbuster drug Cialis, announced that the drug has achieved 1 billion dollars in global sales since launching in Europe less than two years back.
In fact Cialis has become the top Erectile Dysfunction treatment in France, since January 2005, based on the latst market data, easily overtaking Viagra, the first brand to be launched in this market. It is also doing very well in United Kingdom, Italy, Germany, United States, Canada, Australia, Mexico and Brazil.
So much so that a Lilly ICOS press release contained these words from Rich Pilnik, President of Lilly's EMEA region "We are very pleased with the performance of Cialis and the steady development of the brand since its launch two years ago. Millions of men suffer from ED and the growth of the market demonstrates that patients are speaking to their healthcare providers about ED and seeking treatment options."
Not only has Cialis been able to expand the market but it has also eaten heavily in the market share of Viagra from Pfizer, the first drug to be launched in this market and Levitra from Glaxo-Bayer-Schering Plough. In fact Cialis was the second PDE5 inhibitor drug to become available in Europe. It is currently promoted in approximately 100 countries including the United States, Australia, Brazil, Mexico, Canada and across Europe and Asia for Erectile Dysfunction.
According to Paul Clark, Chairman and Chief Executive Officer of ICOS Corporation.
"Passing the $1 billion mark is an important milestone for Lilly ICOS and a great accomplishment for the Cialis team. Since 2003, men with erectile dysfunction have had a choice of oral treatments for their condition - a condition which may impact on relationships and daily life."
Beyond all the hype and the jubilation is the sheer superiority of Cialis over all the other drugs available in this indication. To understand the benefits of Cialis, we need to firstly understand this complex condition.
Erectile Dysfunction or Impotence is defined as the inability to ensure and maintain an erection sufficient for sexual intercourse. ED affects an estimated 180 million men worldwide . 90 percent of ED cases are related to a physical or medical condition, such as diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 percent are due to psychological causes . In many cases, however, both psychological and physical factors contribute to the condition.
Where physical factor play an important role PDE-5( Phosphodiaterase) inhibitors have a significant role to play. These include drugs like Sildenafil (Viagra) and Vardenafil(Levitra). But none are as good as Tadalafil(Cialis). Why?
Firstly let's understand how PDE-5 inhibitors work. They work by inhibiting the enzyme phosphodiasterase-5 which is responsible for degrading another enzyme called cGMP(cyclic Guanosine Mono Phosphate) which through a series of reactions is responsible for the synthesis of nitric oxide. Nitric oxide is an important vasodilator responsible for dilation of the blood vessels that supply blood to the penis. Thus, there is an increase in the blood supplied to the penis and this increased blood engorges the penis and leads the formation of an erection through hydraulic pressure.
All PDE-5 inhibitors work in the same way but because they are different molecules, they also have different properties. The body quickly eliminates both Sildenafil and Vardenafil. Therefore their action lasts for only 4 hours, while Tadalafil(Cialis) is absorbed and eliminated slowly therefore it remains in the body for a longer period of time. Therefore its duration of action is 9 times that of other drugs - 36 hours. This ensures that Cialis will act over a whopping 36 hours and any patient on Cialis does not need to have hurried sex , but sex at his or his partner's leisurely pace. That is why Cialis has been nicknamed as "Le Weekend Pill" in France. It allows the man to relax with his partner and have spontaneous sex.
Also other drugs like Viagra act on the enzyme PDE-6, which is found in the eyes, leading to bluish discolouration of vision, which will not occur with Cialis.
Cialis can be taken with a 100% fat meal and there will be no change in it's action. The same is not true for Sildenafil or Vardenafil, which are affected by food.
All this makes Cialis currently the best drug for erectile dyfunction.
What further adds to it's appeal are programmes like "The Cialis Promise" from Lilly ICOS which guarantees free trial with a rival drug in case Cialis does not work. With this kind of confidence oozing from Lilly ICOS, there is reason to believe in the promise of Cialis.
Cialis is available at any neighbour chemist on providing a doctor's prescription or one can buy Cialis online. An online prescription is generated on filling a short form and on payment through credit card, one can be rest assured of getting Cialis discreetly. What more cheap generic Cialis is also available online. This will further reduce your medical bills. The low cost is like an icing to the Cialis cake or pudding for that matter . But, as is said, the proof of the pudding lies in the eating - So go for Cialis.

Cialis -Top Ten Questions And Answers

What if there are persons who want to use Cialis but are not quite sure of it as there is no source indicated to answer to their problems.Are you interested in this medication and really want to use it? Take a look at these:
1. What does Cialis treat?
Cialis is generally used to treat the difficulties in having and preserving an erection, encountered by men, which also beares the name of impotence.
2. What does Cialis exactly?
What Cialis does is creating some effects produced by some substances in one's body, during the sexual arousal. This has as a result a growth of the blood flow into one's penis. This is what an erection is: the increase of blood flow into the internal areas of the penis.
3. What is the difference between Cialis and other products used for treating the same problems?
The one difference between Cialis and some other products approved by ED is the fact that it persists longer in one's body. Other differences regarding safety or effectiveness which could separate Cialis from other products of its kind have not been studied yet.
4. How should one take Cialis?
Cialis is ought to be taken orally before any sexual act, but it is not advisable to take it more than once a day. It is not necessary to take it after eatting. This is not compulsory.Some patients can support certain changes in the usage of Cialis. anyway one should consult his health care provider.
5.What are the side effects of Cialis if there are any?
Similar to any drug product, side effects may appear. The most frequent ones are:headaches, back pains, muscle pains, stuffy nose or indigestions. These generally persist in the body in between 12 and 24 hors. Problems related to vision have also been reported.
6.What are the facts you definitely need to know about Cialis?
-Cialis can be the cause of a sudden drop of one's blood pressure, if taken along with nitrate medication or alpha-blocker medication( which are used to cure prostatic hyperplasia and also high blood pressure) any other than FLOMAX, 0.4 mg every day. One can feel dizzy, faint or have a stroke.
-One should consult his health care provider if taking Cialis because in the case of heart problems the doctor or health care provider must know when Cialis was last taken.
-One should know that after having used one talet of Cialis, the ingredients may persist in his body for more than two days in the case of liver or kidneys problems, or whenever using other treatment.
7.What should one say to his doctor if he considers it is necessary to take Cialis?
Taking into the fact that the sexual activity is ought to provoke a growth in the heart's work, your doctor should definitely whether Cialis is or is not good for one's heart.In the case of the heart disease named 'left ventricular outlet obstruction' from valvular issues or heart muscles enlargement side effects may appear: fainting, strokes or headaches. Patients who have suffered of heart diseases: anginas, heart failure or strokes, recently, should not take Cialis as long and painful erections may appear. This condition is extremely serious and needs urgent medical attention. In the case of an erection which lasts for more than 4 hours medical attention is needed.
8.What persons are forbidden to take Cialis?
Patients who are using nitrates(nitroglycer) or alpha blockers( excepting for FLOMAX) should not take Cialis because there may appear lower blood pressure which is the cause of fainting or even death in some cases.
9. What if the patient is taking other type of drugs?
In this case, one should discuss with his health care provider or doctor because he is the person who could best advice in this case. However, Cialis is not recommended for persons who are using Nitroglycerins or alpha-blockers.
10. How will one find Cialis?
Cialis can be found as oral tablets in 5mg, 10mg and 20mg strength.
In conclusion, we hope this article comes in hand for the persons who are intending to use Cialis because it is very important to take into account all the facts so that no problems should be en countered.

Cialis-Pluses and Minuses

Clinically Cialis could be ranked number one in terms of effective treatment for erectile dysfunction in men. Why so? That is because when it comes to clinical trial results and side effect analysis of ED drugs Cialis proves its effectiveness better than any other drugs in the same category.
Cialis - pluses
1. Cialis seems to be the best among all other oral treatment for male impotency.
2. Cialis Pharmacy changed the whole dynamics of the ED treatment market because of the magic component called Tadalafil. Tadalafil certainly was placed one notch higher than Sildenafil (component for Viagra). Ask those who buy Cialis! The reason is effectiveness of Cialis. Cialis helps men achieve erection within 30 minutes of intake of the medicine and also lasts much longer (up to 36 hours) than its other competitors.
3. Clinical trials developed on thousands of subjects revealed satisfactory results of 43% up to 86% in improving erections, even in patients with radical prostatectomy surgery or neurological diseases. Clinical trials also show that Cialis improved overall erectile function for men with type 1 or type 2 diabetes.
4. Cialis has no food restrictions.
Cialis - minuses
On one hand Cialis has metamorphosed the ED market as far as ED drugs are concerned, however Sildenafil or Viagra still enjoys the loyalty of 22 million men worldwide and constitute important sales in 110 countries worldwide. So let's quickly go through some of these aspects that would help drive awareness among the general users of Cialis.
1. Cialis has a limitation when it comes to combining dosage along with certain other class of drugs. Nitrates (used in treating chest angina) and alpha-blockers (used in treating prostate problems and high blood pressure) cannot be combined with Cialis or any other ED drugs for that matter. This might lead to a fall in the blood pressure to a danger mark that might risk life of the patient using these drugs.
2. Though Cialis has no food restrictions yet excessive alcohol consumption might affect the general health of the patient consuming Cialis, to the extent of lowering blood pressure and causing dizziness.
3. People who buy Cialis must be aware of the adverse side effects of the drug on the body like, headaches, indigestion, nasal congestion, muscle and back pain and facial flushing. There also have been reports of Priapism (a prolonged and painful erection) and vision disturbances, but the reporting has been very rare. This is one of the main reasons as to why you need to consult a doctor and consider a thorough medical check up before you go ahead and buy Cialis.
People tend to buy Cialis online because of cheap availability. A comparative study suggests 64% positive results in Viagra when compared to Cialis yielding 82% positive results in clinical trials of the respective ED drugs. This explains why men go scouting for buying cheap Cialis or generic Cialis when it comes to selection of ED drugs. But whatever you do always make sure you divulge all the necessary medical history to your physician before he or she goes ahead prescribing Cialis.